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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/2358

Title: MANAGEMENTul afectiunilor HEMATOPOIETICE în timpul sarcinii
Other Titles: MANAGEMENT OF HEMATOPOIETIC DISORDERS DURING PREGNANCY
Authors: Ciurescu, Dan
Moga, Silvia
Burtea, Victoria
Onofrei, Rodica
Popovici, Bianca
Dimienescu, Oana
Keywords: pregnancy
lymphoma
leukaemia
teratogenic
organogenesis
chemotherapy
radiotherapy
Issue Date: 2016
Publisher: Editura Universității Transilvania din Brașov
Series/Report no.: 2/2016;
Abstract: In recent decades, the incidence of malignancy has greatly increased and continues to grow among women of childbearing age. The diagnosis of onco-haematological diseases during pregnancy is made difficult. The most common disorders are: lymphoma and acute leukaemia. Adverse foetal effects of chemotherapy include: foetal death, birth defects, foetal neoplasia, intrauterine growth disorders and mental retardation. Maternal negative effects are those encountered in the general population. The exposure to chemotherapy in the first trimester of pregnancy increases the teratogenic risk between 10-25%. The therapies applied on pregnant women are adapting taking into account the physiological changes produced by the presence of a pregnancy. Most therapeutic schemes need the abortion if the treatment is initiated in the first trimester of pregnancy. In the 2nd or 3rd trimesters of pregnancy, the antineoplastic therapy is initiated using less aggressive therapeutic options.
Description: Jurnal Medical Brașovean,2016.nr.2,p.4-13.ISSN 1841-0782,e-ISSN 2247-4706
URI: http://hdl.handle.net/123456789/2358
ISSN: 1841-0782 e-ISSN 2247-4706
Appears in Collections:Jurnal Medical Brașovean - ARHIVA

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