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Title: | MANAGEMENTul afectiunilor HEMATOPOIETICE în timpul sarcinii |
Other Titles: | MANAGEMENT OF HEMATOPOIETIC DISORDERS DURING PREGNANCY |
Authors: | Ciurescu, Dan Moga, Silvia Burtea, Victoria Onofrei, Rodica Popovici, Bianca Dimienescu, Oana |
Keywords: | pregnancy lymphoma leukaemia teratogenic organogenesis chemotherapy radiotherapy |
Issue Date: | 2016 |
Publisher: | Editura Universității Transilvania din Brașov |
Series/Report no.: | 2/2016; |
Abstract: | In recent decades, the incidence of malignancy has greatly increased and continues to grow among
women of childbearing age. The diagnosis of onco-haematological diseases during pregnancy is made
difficult. The most common disorders are: lymphoma and acute leukaemia. Adverse foetal effects of
chemotherapy include: foetal death, birth defects, foetal neoplasia, intrauterine growth disorders and mental
retardation. Maternal negative effects are those encountered in the general population. The exposure to
chemotherapy in the first trimester of pregnancy increases the teratogenic risk between 10-25%.
The therapies applied on pregnant women are adapting taking into account the physiological changes
produced by the presence of a pregnancy. Most therapeutic schemes need the abortion if the treatment is
initiated in the first trimester of pregnancy. In the 2nd or 3rd trimesters of pregnancy, the antineoplastic
therapy is initiated using less aggressive therapeutic options. |
Description: | Jurnal Medical Brașovean,2016.nr.2,p.4-13.ISSN 1841-0782,e-ISSN 2247-4706 |
URI: | http://hdl.handle.net/123456789/2358 |
ISSN: | 1841-0782 e-ISSN 2247-4706 |
Appears in Collections: | Jurnal Medical Brașovean - ARHIVA
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